Viral Pathogenesis: From Basics to Systems Biology

Viral Pathogenesis: From Basics to Systems Biology

4.5 out of 5

Language	:	English
File size	:	25947 KB
Text-to-Speech	:	Enabled
Screen Reader	:	Supported
Enhanced typesetting	:	Enabled
Print length	:	345 pages

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Viruses are ubiquitous agents that pose a constant threat to the health of individuals and communities worldwide. Understanding the mechanisms by which viruses cause disease is crucial for developing effective strategies for prevention, diagnosis, and treatment. Viral Pathogenesis: From Basics to Systems Biology provides a comprehensive overview of this rapidly evolving field, offering a deep understanding of the fundamental principles and cutting-edge advancements in viral pathogenesis.

Section 1: Foundations of Viral Pathogenesis

This section lays the groundwork for understanding viral pathogenesis, covering essential concepts such as:

• Viral structure and classification
• Mechanisms of viral entry into host cells
• Viral replication strategies
• Host-virus interactions

Section 2: Viral Immune Evasion and Pathogenesis

Viruses have evolved sophisticated strategies to evade the host immune system, enabling them to establish persistent infections and cause disease. This section explores:

• Innate and adaptive immune responses to viral infections
• Viral mechanisms of immune evasion
• Immunopathogenesis and the role of the immune system in viral disease

Section 3: Viral Pathogenesis in Different Organ Systems

Viruses can cause a wide range of diseases affecting various organs and tissues. This section examines the specific mechanisms of viral pathogenesis in different organ systems, including:

• Respiratory system (e.g., influenza, COVID-19)
• Gastrointestinal tract (e.g., norovirus, hepatitis A)
• Nervous system (e.g., rabies, herpes simplex virus)
• Cardiovascular system (e.g., coxsackievirus)

Section 4: Systems Biology Approaches to Viral Pathogenesis

Systems biology integrates multiple disciplines to study complex biological systems, including viral pathogenesis. This section introduces:

• Computational modeling of viral infection and transmission
• Systems-level analysis of host-virus interactions
• Network biology approaches to identify key regulators of viral pathogenesis

Section 5: Emerging and Re-emerging Viral Pathogens

This section explores the challenges posed by emerging and re-emerging viral pathogens, including:

• Origins and drivers of viral emergence
• Pandemic potential of emerging viruses
• Strategies for preparedness and response

Viral Pathogenesis: From Basics to Systems Biology provides a comprehensive and up-to-date overview of this dynamic and rapidly evolving field. By integrating fundamental principles with cutting-edge advancements in systems biology, this book empowers readers to gain a deep understanding of the mechanisms by which viruses cause disease and to contribute to the development of effective interventions for the prevention, diagnosis, and treatment of viral infections.

Viral Pathogenesis: From Basics to Systems Biology

4.5 out of 5

Language	:	English
File size	:	25947 KB
Text-to-Speech	:	Enabled
Screen Reader	:	Supported
Enhanced typesetting	:	Enabled
Print length	:	345 pages

FREE